The SCUBA Legacy Catalogue: Continuum Objects Detected by SCUBA

We present the SCUBA Legacy Catalogues, two comprehensive sets of continuum maps (and catalogues) using data at 850 microns and 450 microns of the various astronomical objects obtained with the Submillimetre Common User Bolometer Array (SCUBA). The Fundamental Map Dataset contains data only where superior atmospheric opacity calibration data were available. The Extended Map Dataset is comprised of data regardless of the quality of the opacity calibration. Each Dataset contains 1.2 degree x 1.2 degree maps at locations where data existed in the JCMT archive, imaged using the matrix inversion method. The Fundamental Dataset is comprised of 1423 maps at 850 microns and 1357 maps at 450 microns. The Extended Dataset is comprised of 1547 maps at 850 microns. Neither Dataset includes high sensitivity, single chop SCUBA maps of "cosmological fields" nor solar system objects. Each Dataset was used to determine a respective Object Catalogue, consisting of objects identified within the respective 850 micron maps using an automated identification algorithm. The Fundamental and Extended Map Object Catalogues contain 5061 and 6118 objects respectively. Objects are named based on their respective J2000 position of peak 850 micron intensity. The Catalogues provide for each object the respective maximum 850 micron intensity, estimates of total 850 micron flux and size, and tentative identifications from the SIMBAD Database. Where possible, the Catalogues als provide for each object its maximum 450 micron intensity and total 450 micron flux, and flux ratios. Data products, machine-readable tables and a full version of the paper can be retrieved at http://www.cadc.hia.nrc.gc.ca/community/scubalegacy .Comment: 41 pages, 17 figures in JPEG format; to be published in ApJ

Thoracoamniotic shunt placement for a right-sided congenital diaphragmatic hernia complicated by hydrops

AbstractMortality associated with congenital diaphragmatic hernia (CDH) is high, and the role of prenatal management continues to evolve. We report a case of a right-sided CDH complicated by fetal hydrops successfully managed with thoracoamniotic shunt placement. Subsequent ultrasounds indicated resolution of hydrops. Despite preterm premature rupture of membrane and preterm delivery at 32 3/7 weeks gestation, the infant survived to hospital discharge at 2.5 months of life. This is the first case of a hydropic right-sided CDH successfully treated with a thoracoamniotic shunt

The translation research in a dental setting (TRiaDS) programme protocol

Background: It is well documented that the translation of knowledge into clinical practice is a slow and haphazard process. This is no less true for dental healthcare than other types of healthcare. One common policy strategy to help promote knowledge translation is the production of clinical guidance, but it has been demonstrated that the simple publication of guidance is unlikely to optimise practice. Additional knowledge translation interventions have been shown to be effective, but effectiveness varies and much of this variation is unexplained. The need for researchers to move beyond single studies to develop a generalisable, theory based, knowledge translation framework has been identified.For dentistry in Scotland, the production of clinical guidance is the responsibility of the Scottish Dental Clinical Effectiveness Programme (SDCEP). TRiaDS (Translation Research in a Dental Setting) is a multidisciplinary research collaboration, embedded within the SDCEP guidance development process, which aims to establish a practical evaluative framework for the translation of guidance and to conduct and evaluate a programme of integrated, multi-disciplinary research to enhance the science of knowledge translation.Methods: Set in General Dental Practice the TRiaDS programmatic evaluation employs a standardised process using optimal methods and theory. For each SDCEP guidance document a diagnostic analysis is undertaken alongside the guidance development process. Information is gathered about current dental care activities. Key recommendations and their required behaviours are identified and prioritised. Stakeholder questionnaires and interviews are used to identify and elicit salient beliefs regarding potential barriers and enablers towards the key recommendations and behaviours. Where possible routinely collected data are used to measure compliance with the guidance and to inform decisions about whether a knowledge translation intervention is required. Interventions are theory based and informed by evidence gathered during the diagnostic phase and by prior published evidence. They are evaluated using a range of experimental and quasi-experimental study designs, and data collection continues beyond the end of the intervention to investigate the sustainability of an intervention effect.Discussion: The TRiaDS programmatic approach is a significant step forward towards the development of a practical, generalisable framework for knowledge translation research. The multidisciplinary composition of the TRiaDS team enables consideration of the individual, organisational and system determinants of professional behaviour change. In addition the embedding of TRiaDS within a national programme of guidance development offers a unique opportunity to inform and influence the guidance development process, and enables TRiaDS to inform dental services practitioners, policy makers and patients on how best to translate national recommendations into routine clinical activities

D-meson semileptonic decays to pseudoscalars from four-flavor lattice QCD

We present lattice-QCD calculations of the hadronic form factors for the semileptonic decays $D\to\pi\ell\nu$, $D\to K\ell\nu$, and $D_s\to K\ell\nu$. Our calculation uses the highly improved staggered quark (HISQ) action for all valence and sea quarks and includes $N_f=2+1+1$ MILC ensembles with lattice spacings ranging from $a\approx0.12$ fm down to $0.042$ fm. At most lattice spacings, an ensemble with physical-mass light quarks is included. The HISQ action allows all the quarks to be treated with the same relativistic light-quark action, allowing for nonperturbative renormalization using partial conservation of the vector current. We combine our results with experimental measurements of the differential decay rates to determine $|V_{cd}|^{D\to\pi}=0.2238(11)^{\rm Expt}(15)^{\rm QCD}(04)^{\rm EW}(02)^{\rm SIB}[22]^{\rm QED}$ and $|V_{cs}|^{D\to K}=0.9589(23)^{\rm Expt}(40)^{\rm QCD}(15)^{\rm EW}(05)^{\rm SIB}[95]^{\rm QED}$ This result for $|V_{cd}|$ is the most precise to date, with a lattice-QCD error that is, for the first time for the semileptonic extraction, at the same level as the experimental error. Using recent measurements from BES III, we also give the first-ever determination of $|V_{cd}|^{D_s\to K}=0.258(15)^{\rm Expt}(01)^{\rm QCD}[03]^{\rm QED}$ from $D_s\to K \ell\nu$. Our results also furnish new Standard Model calculations of the lepton flavor universality ratios $R^{D\to\pi}=0.98671(17)^{\rm QCD}[500]^{\rm QED}$, $R^{D\to K}=0.97606(16)^{\rm QCD}[500]^{\rm QED}$, and $R^{D_s\to K}=0.98099(10)^{\rm QCD}[500]^{\rm QED}$, which are consistent within $2\sigma$ with experimental measurements. Our extractions of $|V_{cd}|$ and $|V_{cs}|$, when combined with a value for $|V_{cb}|$, provide the most precise test of second-row CKM unitarity, finding agreement with unitarity at the level of one standard deviation.Comment: 92 page

Outcomes in pediatric studies of medium-chain acyl-coA dehydrogenase (MCAD) deficiency and phenylketonuria (PKU): a review.

BACKGROUND: Inherited metabolic diseases (IMDs) are a group of individually rare single-gene diseases. For many IMDs, there is a paucity of high-quality evidence that evaluates the effectiveness of clinical interventions. Clinical effectiveness trials of IMD interventions could be supported through the development of core outcome sets (COSs), a recommended minimum set of standardized, high-quality outcomes and associated outcome measurement instruments to be incorporated by all trials in an area of study. We began the process of establishing pediatric COSs for two IMDs, medium-chain acyl-CoA dehydrogenase (MCAD) deficiency and phenylketonuria (PKU), by reviewing published literature to describe outcomes reported by authors, identify heterogeneity in outcomes across studies, and assemble a candidate list of outcomes. METHODS: We used a comprehensive search strategy to identify primary studies and guidelines relevant to children with MCAD deficiency and PKU, extracting study characteristics and outcome information from eligible studies including outcome measurement instruments for select outcomes. Informed by an established framework and a previously published pediatric COS, outcomes were grouped into five, mutually-exclusive, a priori core areas: growth and development, life impact, pathophysiological manifestations, resource use, and death. RESULTS: For MCAD deficiency, we identified 83 outcomes from 52 articles. The most frequently represented core area was pathophysiological manifestations, with 33 outcomes reported in 29/52 articles (56%). Death was the most frequently reported outcome. One-third of outcomes were reported by a single study. The most diversely measured outcome was cognition and intelligence/IQ for which eight unique measurement instruments were reported among 14 articles. For PKU, we identified 97 outcomes from 343 articles. The most frequently represented core area was pathophysiological manifestations with 31 outcomes reported in 281/343 articles (82%). Phenylalanine concentration was the most frequently reported outcome. Sixteen percent of outcomes were reported by a single study. Similar to MCAD deficiency, the most diversely measured PKU outcome was cognition and intelligence/IQ with 39 different instruments reported among 82 articles. CONCLUSIONS: Heterogeneity of reported outcomes and outcome measurement instruments across published studies for both MCAD deficiency and PKU highlights the need for COSs for these diseases, to promote the use of meaningful outcomes and facilitate comparisons across studies

Instructions to BBF RFC Authors

This BioBricks Foundation Request for Comments (BBF RFC) provides in- formation about the preparation and submission of BBF RFCs to The Bio- Bricks Foundation (BBF)

The role of soil chemistry in wine grape quality and sustainable soil management in vineyards

This study aimed to establish if there is any evidence that soil mineralogical and/or chemical composition influence the composition and quality of wine grapes. In the initial phase of the study, soils and grapes were sampled in two riesling vineyards i

Longwood Range Platinum, Southland

The Longwood Range includes extensive outcrops of the Hekeia Gabbro, a Permian mafic-ultramafic layered plutonic complex that was intruded into Permian Brook Street Terrane volcanogenic sediments. Analyses of core from drill holes in the Hekeia Gabbro show that there is localised enrichment in platinum group elements (PGE), but no PGE minerals have yet been identified. The most PGE-enriched rocks are gabbros and troctolites, rather than the most ultramafic rocks, which are plagioclase wehrlites. Cr-spinels and magmatic sulfides (pyrrhotite, chalcopyrite, pentlandite) are rare and show no evidence of accumulations in association with PGE enrichment zones. The Hekeia Gabbro is extensively altered in places to amphibolite facies and/ or greenschist facies assemblages. There has been minor remobilisation and localised enrichment of Pt, Pd and/ or Cu in association with some of this alteration. Primary igneous magnetite was replaced during alteration, and alteration magnetite has formed in some zones, especially in association with serpentinised olivine. Detrital isoferroplatinum, sperry lite, Os-Ru-lr alloys and cooperite-braggite solid solution minerals occur in palaeoplacers on the southern slopes of the Hekeia Gabbro. The cooperite-braggite solid solution minerals have low Ni, typical of Ural-Alaska complexes, and the Os-Ru-Ir alloy particles are only incipiently rounded, suggesting that they may have been sourced nearby, from the Hekeia Gabbro. The Hekeia Gabbro, and other similar mafic-ultramafic bodies in the Brook Street Terrane, and their correlatives in Australia, are apparently fertile sites for PGE enrichment